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Journal / Cancer Research / Um modelo de linfoma de célula B Syngeneic Mouse…
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Cancer Research

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JoVE Journal Cancer Research
Um modelo de linfoma de célula B Syngeneic Mouse para avaliação pré-clínica de pilhas de T de carro CD19
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Um modelo de linfoma de célula B Syngeneic Mouse para avaliação pré-clínica de pilhas de T de carro CD19

Article DOI: 10.3791/58492-v • 12:16 min • October 16th, 2018
October 16th, 2018 •
1, 1, 1, 1,2, 1
1Manchester Cancer Research Centre Building, Department Cancer Sciences, University of Manchester, 2Celyad

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Aqui, apresentamos um protocolo para a produção e testes pré-clínicos de murino células CD19 carro T por transdução retroviral e utilização como uma terapia contra linfoma de célula B A20 syngeneic estabelecida em camundongos BALB/c com ou sem lymphodepleting pré-condicionamento.

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Pesquisa sobre o câncer questão 140 carro T células caminhões adotiva T-terapia celular syngeneic mouse-imunoterapia modelo A20 IL-12 pré-condicionamento CD19 linfoma
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