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器官型培养的神经元雪崩多电极阵列记录
JoVE Journal
Neuroscience
This content is Free Access.
JoVE Journal Neuroscience
Multi-electrode Array Recordings of Neuronal Avalanches in Organotypic Cultures
DOI:

16:01 min

August 01, 2011

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Chapters

  • 00:05Title
  • 02:09Preparation of a Glass Chamber with Integrated Microelectrode Arrays (MEA)
  • 05:00Cortex and Ventral Tegmental Area (VTA) Tissue Dissection
  • 08:46Mounting Cortex and VTA Tissue Slices on the MEA
  • 11:20Electrophysiological Recording of Spontaneous and Stimulus-Evoked Neural Activity
  • 13:38MEA Recording Results
  • 15:31Conclusion

Summary

Automatic Translation

一个可靠的方法来研究神经元雪崩,即规模不变的时空活动突发,在大脑皮层的临界状态动力学指示。雪崩出现自发的发展培养皮层的表面层与平面集成多电极阵列(MEA)的精确控制的条件下允许活动的长期测量。

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