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Robust Generation of Hepatocyte-like Cells from Human Embryonic Stem Cell Populations

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Biology

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JoVE Journal Biology

Robust Generation of Hepatocyte-like Cells from Human Embryonic Stem Cell Populations

Robust Generation of Hepatocyte-like Cells from Human Embryonic Stem Cell Populations

DOI:

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05:49 min

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October 26, 2011

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Claire N. Medine, Baltasar Lucendo-Villarin, Wenli Zhou, Christopher C. West, David C. Hay

¹Medical Research Council Centre for Regenerative Medicine,University of Edinburgh

Chapters

00:05Title
01:35Priming Human ESCs to Definitive Endoderm and Specifying Hepatic Endoderm
03:58Functional Characterization of Hepatic Endoderm
04:55Characterizing the Human ESC Differentiation to Hepatic Endoderm
05:14Conclusion

Summary

Automatic Translation

This article will focus on the generation of human hepatic endoderm from human embryonic stem cell populations.

Tags

Human Embryonic Stem Cells Hepatocyte-like Cells Drug Toxicity Predictive Toxicology Screens Clinical Trials Drug Development Human Hepatocytes Immortalized Cell Lines Pluripotent Stem Cells (PSCs)Self Renewal Differentiation Somatic Cell Types Inexhaustible Source Functional Human HLCs Automation Scalable Production Drug Discovery Disease Modeling

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