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JoVE Journal
Immunology and Infection
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Granulocyt-beroende autoantikroppar-inducerad hudblåsor
 
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Granulocyt-beroende autoantikroppar-inducerad hudblåsor

Article DOI: 10.3791/4250
October 12th, 2012

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Summary October 12th, 2012

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I djurmodellen som beskrivs i vårt nuvarande arbete, renade IgG-antikroppar mot en sträcka av 200 aminosyror (aa 757-967) av kollagen VII injiceras upprepade gånger i möss återger blåsbildning fenotypen samt histo-och immunopatologiska egenskaper karakteristiska för humant epidermolysis bullosa acquisita (EBA)

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