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允许有针对性的大鼠模型血 - 脑屏障破坏神经血管治疗
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JoVE Journal
Medicine
Rat Model of Blood-brain Barrier Disruption to Allow Targeted Neurovascular Therapeutics
Please note that all translations are automatically generated.
Click here for the English version.
允许有针对性的大鼠模型血 - 脑屏障破坏神经血管治疗
DOI:
10.3791/50019-v
•
08:43 min
•
November 30, 2012
•
Jacob A. Martin
,
Alexander S. Maris
,
Moneeb Ehtesham
,
Robert J. Singer
1
Department of Neurological Surgery
,
Vanderbilt University School of Medicine
Chapters
00:05
Title
01:40
Intubate the Rat
03:21
Establish IV Anesthesia
04:17
Expose the Bifurcation of the Common Carotid Artery and Catherize the External Carotid Artery
07:38
Representative Blood-brain Barrier Disruption
08:12
Conclusion
Summary
Automatic Translation
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Automatic Translation
血 - 脑屏障破坏,帮助某些药物输送到大脑。甘露醇动脉内交付收缩血管周围的细胞,以扰乱障碍。
Tags
Blood-brain Barrier
Neurovascular Therapeutics
Endothelial Cells
Tight Junctions
Blood-brain Barrier Disruption
Osmotic Disruption
Mannitol
Pharmacological Disruption
Focused Ultrasound
Microbubbles
Intracerebral Infusion
Translational Research
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