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RNA secundaire structuur Voorspelling behulp van High-throughput SHAPE
 
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RNA secundaire structuur Voorspelling behulp van High-throughput SHAPE

Article DOI: 10.3791/50243
May 31st, 2013

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Summary May 31st, 2013

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High-throughput selectieve 2-hydroxyl acylering geanalyseerd door primerverlenging (SHAPE) gebruikt een nieuwe chemische indringende techniek, reverse transcriptie, capillaire elektroforese en secundaire structuur predictie software om de structuren van RNA bepalen van enkele honderden tot enkele duizenden nucleotiden aan nucleotide resolutie.

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