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Journal
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Medicine
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注射原位乳腺癌细胞到小鼠乳腺脂肪垫来研究肿瘤的生长。
JoVE Journal
Medicine
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JoVE Journal
Medicine
Orthotopic Injection of Breast Cancer Cells into the Mammary Fat Pad of Mice to Study Tumor Growth.
Please note that all translations are automatically generated.
Click here for the English version.
注射原位乳腺癌细胞到小鼠乳腺脂肪垫来研究肿瘤的生长。
DOI:
10.3791/51967-v
•
07:52 min
•
February 08, 2015
•
Begüm Kocatürk
,
Henri H. Versteeg
1
Department of Hemostasis and Thrombosis
,
Leiden University Medical Center
Chapters
00:05
Title
01:23
Cell, Mouse, and Instrument Preparation
02:34
Orthotopic Injection
04:19
Organ Harvest
05:39
Results: Representative Othotopic and Metastatic Breast Tumor Growth in Mice
07:25
Conclusion
Summary
Automatic Translation
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Automatic Translation
癌症是受肿瘤周围的组织,以及本地亲和抗炎介质影响的复杂疾病。因此,正交注入模式的,而不是皮下模型可能是有用的,研究癌症进展的方式,更好地模拟人类的病理。
Tags
Breast Cancer
Orthotopic Injection
Mammary Fat Pad
Mouse Model
Tumor Growth
Genetic Manipulation
Stromal Compartment
Cancer Cell Engraftment
Tumor Analysis
Metastasis
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