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Journal / Neuroscience / Modelleme nöronal ölüm ve fare birincil…
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JoVE Journal Neuroscience
Modelleme nöronal ölüm ve fare birincil serebellar granül nöronlar dejenerasyon
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Modelleme nöronal ölüm ve fare birincil serebellar granül nöronlar dejenerasyon

Article DOI: 10.3791/55871-v • 10:36 min • November 6th, 2017
November 6th, 2017 •
1,2, 1, 3, 1,2,4
1Lady Davis Institute for Medical Research, Jewish General Hospital, 2Integrated Program in Neuroscience, McGill University, 3Department of Cellular and Molecular Medicine, University of Ottawa, 4Department of Oncology, Faculty of Medicine, McGill University

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Bu iletişim kuralı yalıtma ve birincil fare serebral granül neurons (CGNs) 6-7 gün eski pups, CGNs kaybı için verimli iletim ve kazanç işlevi çalışmalar, kültür ve nöronal excitotoxicity NMDA kaynaklı modelleme için basit bir yöntem açıklar, düşük potasyum indüklenen hücre ölümü, DNA hasarı ve oksidatif stres aynı kültür modelini kullanarak.

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Neuroscience sayı: 129 beyincik serebellar granül nöronlar (CGN) Adenovirus Lentiviral iletim Excitotoxicity N-metil-D-Aspartat (NMDA) Apoptozis Potasyum klorür (KCl) Camptothecin hidrojen peroksit (H2O2)
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