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Journal / Cancer Research / Inducción y diagnóstico de tumores en
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JoVE Journal Cancer Research
Inducción y diagnóstico de tumores en
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Inducción y diagnóstico de tumores en

Article DOI: 10.3791/55901-v • 08:14 min • July 25th, 2017
July 25th, 2017 •
1,2, 1
1Structural Biology Center, National Institute of Genetics and Department of Genetics, School of Life Science, SOKENDAI, 2Graduate School of Media and Governance, Keio University

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El análisis de clones mosaicos en el epitelio discal imaginario de Drosophila es un poderoso sistema modelo para estudiar los mecanismos genéticos y celulares de la tumorigénesis. Aquí se describe un protocolo para inducir tumores en Drosophila ala imaginal discos utilizando el sistema GAL4-UAS, e introducir un método de diagnóstico para clasificar los tumores fenotipos.

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Biología del Cáncer Número 125 Drosophila Disco Imaginal Tumorigénesis Neoplasia Displasia Gen supresor de tumores GAL4-UAS RNAi
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