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Bioengineering
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用于内皮靶向和药物传递的功能化10纳米高分子涂层金粒子的合成
JoVE Journal
Bioengineering
This content is Free Access.
JoVE Journal
Bioengineering
Synthesis of Functionalized 10-nm Polymer-coated Gold Particles for Endothelium Targeting and Drug Delivery
Please note that all translations are automatically generated.
Click here for the English version.
用于内皮靶向和药物传递的功能化10纳米高分子涂层金粒子的合成
DOI:
10.3791/56760-v
•
10:38 min
•
January 15, 2018
•
Ming J. Cheng
,
Priya Prabakaran
,
Rajiv Kumar
3
,
Srinivas Sridhar
2,3
,
Eno E. Ebong
4,5
1
Department of Chemical Engineering
,
Northeastern University
,
2
Nanomedicine Science and Technology Center
,
Northeastern University
,
3
Department of Physics
,
Northeastern University
,
4
Departments of Bioengineering
,
Northeastern University
,
5
Department of Neuroscience
,
Albert Einstein College of Medicine
Chapters
00:05
Title
00:38
Synthesis of Polyethylene Glycol-coated Gold Nanoparticles (PEG-AuNPs)
03:13
Conjugation of Fluorophores onto the PEG-AuNP NH
2
Groups
04:56
Characterization of Fluorescent PEG-AuNPs
08:46
Results: Size and Biocompatibility of THPC-coated and Fluorescent PEG-AuNPs
10:19
Conclusion
Summary
Automatic Translation
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Automatic Translation
我们描述了一种合成具有生物相容性的10纳米金纳米粒子的方法, 其功能是在表面上涂上聚乙二醇。这些微粒可以使用
在体外
和
在体内
提供治疗的纳米细胞和细胞外空间, 难以获得常规纳米颗粒的大小。
Tags
Gold Nanoparticles
Polymer Coating
Functionalization
Endothelium Targeting
Drug Delivery
Biocompatibility
Fluorescence Imaging
THPC
Chloroauric Acid
PEG
Dialysis
Lyophilization
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