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Avaliação global da eficácia e segurança de entrega de droga Placenta-alvo usando três métodos complementares
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1Laboratory for Reproductive Health, Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology,Chinese Academy of Sciences, 2College of Veterinary Medicine,Hunan Agricultural University, 3Key Laboratory of Chemical Engineering Process and Technology for High-efficiency Conversion, College of Chemistry and Material Sciences,Heilongjiang University, 4Department of Obstetrics and Gynecology,Wayne State University School of Medicine
Chapters
- 00:04Title
- 01:11In Vivo Fluorescence Imaging
- 02:35High-Frequency Ultrasound (HFUS) Embryonic Development Evaluation
- 04:28High Pressure Liquid Chromatography (HPLC) Analysis
- 06:18Results: Representative Placenta-Targeted Drug Delivery Analyses
- 08:12Conclusion
Descrevemos um sistema que utiliza três métodos para avaliar a segurança e a eficácia da entrega da droga placenta-alvo: no vivo de imagem para monitorar o acúmulo de nanopartículas, ultra-som de alta frequência para monitorar o desenvolvimento placentário e fetal e HPLC para quantificar a entrega da droga ao tecido.
