Digital Spatial Profiling for Characterization of the Microenvironment in Adult-Type Diffusely Infiltrating Glioma

Digital Spatial Profiling, or DSP, offers an efficient method for spatially stratified protein quantification. Its implementation enables us to characterize protein expression across distinct regions of a tumor and the microenvironment. A key feature of DSP is its multiplexing capability, enabling high throughput data processing.

The ability to define customized regions of interest additionally provides a spatial dimension to data analysis. DSP can be applied to any sample in which spatially quantifying protein, or RNA expression may help elucidate a pathologic, or physiologic process. This is especially relevant in oncology, where regional target variability may correlate with malignant growth, or invasion.