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常温心脏骤停和心肺复苏术：缺血再灌注损伤的小鼠模型

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JoVE Journal Medicine

Normothermic Cardiac Arrest and Cardiopulmonary Resuscitation: A Mouse Model of Ischemia-Reperfusion Injury

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常温心脏骤停和心肺复苏术：缺血再灌注损伤的小鼠模型

DOI:

•

10:25 min

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August 30, 2011

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Michael P. Hutchens, Richard J. Traystman, Tetsuhiro Fujiyoshi, Shin Nakayama, Paco S. Herson

¹Department of Anesthesiology and Perioperative Medicine,Oregon Health & Sciences University, ²Department of Pharmacology,University of Colorado Denver

Chapters

00:05Title
01:32Surgical Preparation
03:47Cardiac Arrest
06:53Perfusion, Fixation and Kidney Harvest
07:19Assessment of Murine Renal Damage after CA/CPR
10:00Conclusion

Summary

Automatic Translation

一个强大的围手术期和关键护理相关的急性肾损伤模型。使用近复制临床AKI的组织学和功能的变化有可能诱发心脏骤停的全身血流灌注不足。

Tags

Normothermic Cardiac Arrest Cardiopulmonary Resuscitation Mouse Model Ischemia-reperfusion Injury Acute Kidney Injury Critical Illness Whole-body Hypoperfusion Rodent Models Focal Ischemia Genetic Manipulation Cardiac Arrest And Cardiopulmonary Resuscitation Model Physiologic Outcomes Functional Outcomes Anatomic Outcomes Histologic Outcomes Murine Surgical Model Organ-specific Outcomes

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