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Effects of Exposure of Formaldehyde to a Rat Model of Atopic Dermatitis Induced by Neonatal Capsaicin Treatment
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Immunology and Infection
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JoVE Journal Immunology and Infection
Effects of Exposure of Formaldehyde to a Rat Model of Atopic Dermatitis Induced by Neonatal Capsaicin Treatment

Effects of Exposure of Formaldehyde to a Rat Model of Atopic Dermatitis Induced by Neonatal Capsaicin Treatment

DOI:
10.3791/55987-v

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06:47 min

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September 27, 2017

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, , , , ,
1Neuroscience Research Institute & Department of Physiology, College of Medicine,Korea University, 2Department of Pharmaceutics and Biotechnology, College of Medical Engineering,Konyang University, 3Division of Biological Science and Technology, Science and Technology College,Yonsei University Wonju Campus

Chapters

  • 00:05Title
  • 00:43Induction of Atopic Dermatitis (AD) by Neonatal Capsaicin Treatment
  • 01:48Measurement of Pruritus by Counting Spontaneous Scratching Behavior
  • 02:53Exposure of Animals to Gaseous Formaldehyde
  • 04:22Results: Capsaicin and Formaldehyde Treatment Induces and Aggravates Relapsing AD-line Skin Inflammation and Pruritus in Rats
  • 06:11Conclusion

Summary

Automatic Translation

Automatic Translation

We describe here methods for neonatal capsaicin treatment to induce atopic dermatitis in rats and exposure of vaporized formaldehyde to investigate the effects of formaldehyde inhalation on atopic dermatitis.

Tags

Atopic DermatitisNeonatal Capsaicin TreatmentFormaldehyde ExposureRat ModelSkin LesionsScratching BehaviorPathophysiologySubcutaneous InjectionSprague Dawley RatsVideo RecordingSkin Lesion Scoring

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