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Neuroscience

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Purkinje Cell Survival in Organotypic Cerebellar Slice Cultures
 

Purkinje Cell Survival in Organotypic Cerebellar Slice Cultures

Article DOI: 10.3791/60353-v
December 18th, 2019

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Summary December 18th, 2019

Organotypic slice cultures are a powerful tool to study neurodevelopmental or degenerative/regenerative processes. Here, we describe a protocol that models the neurodevelopmental death of Purkinje cells in mouse cerebellar slice cultures. This method may benefit research in neuroprotective drug discovery.

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