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Multiplexed Analysis of Retinal Gene Expression and Chromatin Accessibility Using scRNA-Seq and scATAC-Seq
JoVE Journal
Neuroscience
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JoVE Journal Neuroscience
Multiplexed Analysis of Retinal Gene Expression and Chromatin Accessibility Using scRNA-Seq and scATAC-Seq
DOI:

06:24 min

March 12, 2021

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Chapters

  • 00:04Introduction
  • 00:47Cell Barcoding
  • 03:23Paired scRNA-seq and scATAC-seq
  • 04:40Results: Multiplexed Analysis Using scRNA-Seq and scATAC-Seq for Characterization of Cell Origin, Phenotype and Gene Regulatory Networks
  • 05:45Conclusion

Summary

Automatic Translation

Here, the authors showcase the utility of MULTI-seq for phenotyping and subsequent paired scRNA-seq and scATAC-seq in characterizing the transcriptomic and chromatin accessibility profiles in retina.

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