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Journal / Neuroscience / scRNA-SeqおよびscATAC-Seqを用いた網膜遺伝子発現およびクロマチンアクセシビリティの…
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Neuroscience

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JoVE Journal Neuroscience
scRNA-SeqおよびscATAC-Seqを用いた網膜遺伝子発現およびクロマチンアクセシビリティの多重化解析
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scRNA-SeqおよびscATAC-Seqを用いた網膜遺伝子発現およびクロマチンアクセシビリティの多重化解析

Article DOI: 10.3791/62239-v • 06:24 min • March 12th, 2021
March 12th, 2021 •
*1, *1, 1, 1,2,3,4,5,6
1Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, 2Department of Psychiatry and Behavioral Science, The Johns Hopkins Hospital, 3Department of Ophthalmology, The Johns Hopkins Hospital, 4Department of Neurology, The Johns Hopkins Hospital, 5Institute for Cell Engineering, Johns Hopkins University School of Medicine, 6Kavli Neuroscience Discovery Institute, Johns Hopkins University School of Medicine
* These authors contributed equally

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ここで著者らは、網膜におけるトランスクリプトームおよびクロマチンアクセシビリティプロファイルを特徴付ける際の表現型決定およびその後のscRNA-seqおよびscATAC-seqのペアに対するMULTI-seqの有用性を示す。

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神経科学 第169号 発達 疾患 scRNA-Seq scATAC-Seq MULTI-Seq マルチプレックス クロマチン
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