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Journal / Neuroscience / Analisi multiplexata dell'espressione genica…
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JoVE Journal Neuroscience
Analisi multiplexata dell'espressione genica retinica e dell'accessibilità alla cromatina utilizzando scRNA-Seq e scATAC-Seq
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Analisi multiplexata dell'espressione genica retinica e dell'accessibilità alla cromatina utilizzando scRNA-Seq e scATAC-Seq

Article DOI: 10.3791/62239-v • 06:24 min • March 12th, 2021
March 12th, 2021 •
*1, *1, 1, 1,2,3,4,5,6
1Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, 2Department of Psychiatry and Behavioral Science, The Johns Hopkins Hospital, 3Department of Ophthalmology, The Johns Hopkins Hospital, 4Department of Neurology, The Johns Hopkins Hospital, 5Institute for Cell Engineering, Johns Hopkins University School of Medicine, 6Kavli Neuroscience Discovery Institute, Johns Hopkins University School of Medicine
* These authors contributed equally

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Qui, gli autori mostrano l'utilità di MULTI-seq per la fenotipizzazione e il successivo accoppiato scRNA-seq e scATAC-seq nel caratterizzare i profili di accessibilità trascrittomica e cromatina nella retina.

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Neuroscienze Numero 169 Sviluppo Malattia scRNA-Seq scATAC-Seq MULTI-Seq multiplex Cromatina
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