Identificação de sinalização intracelular Eventos induzida em células viáveis pela interação com as células vizinhas Submetidos a apoptose celular Morte
05:27Stimulation of Responder Cells with Apoptotic and Necrotic Cells
07:03Results: Inhibition of Phosphorylation of GSK3α/β in BU.MPT Responder Cells Following Exposure to Apoptotic Cells Requires Direct Cell-cell Interaction but Is Independent of Phagocytosis
Here, we present a protocol for the determination of intracellular signaling events induced in viable cells by physical interaction with adjacent dead or dying cells. The protocol focuses on signaling events induced by receptor-mediated recognition of the dead cells, as opposed to their phagocytic uptake or release of soluble mediators.