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DOVO Generatie van somatische stamcellen door YAP/TAZ
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DOVO Generatie van somatische stamcellen door YAP/TAZ

Article DOI: 10.3791/57462-v • 13:05 min • May 7th, 2018
May 7th, 2018 •
1, 1, 1, 1, 1, 1
1Department of Molecular Medicine, University of Padua School of Medicine

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Beschikbaarheid van somatische SCs is van cruciaal belang voor regeneratieve geneeskunde, ziekte modellering en inzicht te krijgen in de eigenschappen van de SC. Hier presenteren we experimentele strategieën om te herprogrammeren, in vitro, gedifferentieerde volwassen cellen in hun overeenkomstige uitbreidbaar weefsel-specifieke stam/voorlopercellen door de voorbijgaande uitdrukking van de enkele transcriptionele co activator YAP.

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Biologie kwestie 135 YAP/TAZ herprogrammering weefsel-specifieke stamcellen melkklier alvleesklier organoids dedifferentiation
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