00:45Native MS Acquisition and Analysis for Investigating Protein Complexes and Protein-Ligand Complexes
03:51Acquiring and Analyzing IM-MS
04:34In-Solution Disruption of Protein Complexes for Native MS and IM-MS Led Structure Determination and Investigating Protein Complex Stability using Collision Induced Unfolding
05:45Results: Integrative Structural Mass Spectrometry of Protein Architectures and Protein-Ligand Complexes
Massespektrometri (MS) har dukket opp som en viktig verktøy for å undersøke strukturen og dynamikken i macromolecular samlinger. Her integrere vi-baserte tilnærminger til å forhøre protein kompleks dannelse og ligand binding.