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JoVE Journal
Biology

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DamID-SEQ:蛋白质-DNA相互作用的全基因组映射腺嘌呤甲基化的DNA片段通过高通量测序
 
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DamID-SEQ:蛋白质-DNA相互作用的全基因组映射腺嘌呤甲基化的DNA片段通过高通量测序

Article DOI: 10.3791/53620-v 09:14 min January 27th, 2016
January 27th, 2016

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Summary

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Click here for the English version.

我们描述这里的一个检测通过结合DNA腺嘌呤甲基识别(DamID),以高通量测序(DamID-SEQ)。这种改进的方法提供了更高的分辨率和更宽的动态范围,并允许在分析与其他高通量测序数据如芯片起,RNA测序一起DamID-SEQ数据

Tags

分子生物学,第107,脱氧核糖核酸腺嘌呤甲基识别(DamID),DamID-以次,下一代测序,高通量测序,蛋白质-DNA相互作用,核纤层
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